Description

4-(But-3-Yn-1-Yl)Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its unique alkyne-substituted piperidine structure, which is critical for constructing complex molecules in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of potential therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.
• Organic Synthesis Building Block: Used in click chemistry (via the terminal alkyne group) and other coupling reactions to introduce the piperidine moiety into more complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Used for methodological studies and as a reference standard in analytical chemistry.

Basic Information

Product Name	4-(But-3-Yn-1-Yl)Piperidine Hydrochloride
CAS No.	1885090-83-4
Molecular Formula	C9H15N•HCl
Molecular Weight	173.68 g/mol (Free base: 137.22 g/mol)
Synonyms	4-(But-3-yn-1-yl)piperidine hydrochloride; 4-(3-Butynyl)piperidine HCl; 1-(Piperidin-4-yl)but-3-yne hydrochloride; 4-But-3-ynylpiperidine hydrochloride; Piperidine, 4-(3-butyn-1-yl)-, hydrochloride; But-3-yn-1-yl-piperidine-4-yl hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(But-3-Yn-1-Yl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.