Description

Spiro[1,5-Benzoxazepine-3(2H),1'(2'H)-Naphthalene]-7-Carboxylic Acid, 6'-Chloro-3',4,4',5-Tetrahydro-, (1'S)- is a complex spirocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical high-purity building block for synthesizing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) or other therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the complex multi-step synthesis of target APIs, leveraging its unique spirocyclic and benzoxazepine scaffold.
• Medicinal Chemistry Research: Employed as a core structural motif for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Serves as a specialized intermediate for the manufacture of other high-value, complex organic molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	Spiro[1,5-Benzoxazepine-3(2H),1'(2'H)-Naphthalene]-7-Carboxylic Acid, 6'-Chloro-3',4,4',5-Tetrahydro-, (1'S)-
CAS No.	1883726-83-7
Molecular Formula	C21H18ClNO3
Molecular Weight	367.83 g/mol
Synonyms	(1'S)-6'-Chloro-3',4,4',5-tetrahydrospiro[1,5-benzoxazepine-3(2H),1'(2'H)-naphthalene]-7-carboxylic acid; 6'-Chloro-3',4,4',5-tetrahydrospiro[1,5-benzoxazepine-3(2H),1'(2'H)-naphthalene]-7-carboxylic acid, (1'S)-; Spiro[1,5-benzoxazepine-3(2H),1'(2'H)-naphthalene]-7-carboxylic acid, 6'-chloro-3',4,4',5-tetrahydro-, (1'S)-; CAS 1883726-83-7
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions at a controlled room temperature (15-25°C). For long-term storage, consider desiccants or an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.