Description

Benzene, 1-Bromo-4-Chloro-2-Propoxy- (CAS NO 1881331-84-5) is a specialized halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring bromo, chloro, and propoxy substituents on a benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the precise introduction of functional groups and structural motifs critical for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the specific halogen pattern is essential for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of monomers or functional units for advanced polymers, liquid crystals, or organic electronic materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it a valuable substrate for sequential Suzuki, Stille, or Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	Benzene, 1-Bromo-4-Chloro-2-Propoxy-
CAS No.	1881331-84-5
Molecular Formula	C9H10BrClO
Molecular Weight	249.53 g/mol
Synonyms	1-Bromo-4-chloro-2-propoxybenzene; 2-Bromo-5-chloro-1-propoxybenzene; 4-Bromo-1-chloro-2-propoxybenzene; 2-Propoxy-1-bromo-4-chlorobenzene; 1-Chloro-4-bromo-2-propoxybenzene; 4-Chloro-1-bromo-2-propoxybenzene; (2-Bromo-5-chlorophenoxy)propane
EINECS	Contact for details

Quality Control

Our Benzene, 1-Bromo-4-Chloro-2-Propoxy- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are fully characterized, and Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. We adhere to relevant industry standards for fine chemical intermediates to support our global clientele in critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.