Description

4-(Benzyloxy)-3-Chloro-5-Fluorophenol is a high-purity, multi-functional phenolic intermediate featuring a benzyl-protected hydroxyl group and halogen substituents. This compound matters for its role as a versatile building block in the synthesis of complex molecules, offering chemists precise control over molecular architecture. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Serves as a precursor in the design and production of advanced herbicides, fungicides, and pesticides, leveraging the halogenated phenolic structure.
• Liquid Crystal & OLED Material Research: Used in the development of novel organic electronic materials due to its stable, substituted aromatic core which can influence mesogenic and electroluminescent properties.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, such as polyarylates or epoxy resins, to impart specific thermal or chemical resistance.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies in organic synthesis, including cross-coupling reactions and protective group chemistry.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex dyes and pigments where halogen and ether functionalities are required for color fastness and specific spectral properties.

Basic Information

Product Name	4-(Benzyloxy)-3-Chloro-5-Fluorophenol
CAS No.	1881289-00-4
Molecular Formula	C13H10ClFO2
Molecular Weight	252.67 g/mol
Synonyms	3-Chloro-5-fluoro-4-(phenylmethoxy)phenol; 4-(Benzyloxy)-3-chloro-5-fluorophenol; 3-Chloro-5-fluoro-4-(benzyloxy)phenol; Phenol, 4-(benzyloxy)-3-chloro-5-fluoro-; BCFP (abbreviation); 1881289-00-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-(Benzyloxy)-3-Chloro-5-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.