Description

(4As,7As)-Octahydropyrrolo[3,4-B]Morpholine Dihydrochloride is a high-purity, specialized heterocyclic building block and pharmaceutical intermediate. This compound is critical for advanced research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic discovery.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes from milligram to kilogram scale for preclinical and clinical trials.
• Library Synthesis: A valuable reactant for creating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	(4As,7As)-Octahydropyrrolo[3,4-B]Morpholine Dihydrochloride
CAS No.	1881275-73-5
Molecular Formula	C8H16N2O · 2HCl
Molecular Weight	229.14 g/mol (free base: 156.23 g/mol)
Synonyms	Octahydropyrrolo[3,4-b]morpholine dihydrochloride; (4aR,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine-1,3(2H)-dione dihydrochloride (related isomer); Pyrrolomorpholine dihydrochloride; Bicyclic morpholine derivative; CAS 1881275-73-5; 1H-Pyrrolo[3,4-b]pyridine, hexahydro-, dihydrochloride (parent structure); Pharmaceutical intermediate 1881275-73-5.
EINECS	Contact for details

Quality Control

Our (4As,7As)-Octahydropyrrolo[3,4-B]Morpholine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and analytical methods (HPLC, NMR) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.