Description

m-Peg4-Phosphonic Acid CAS NO 1872433-62-9 is a specialized bifunctional chemical building block that combines a phosphonic acid group with a tetraethylene glycol (PEG4) spacer. This molecular architecture is critical for creating stable, water-soluble conjugates and surface modifications in advanced material science and bioconjugation. It is an essential reagent for researchers and manufacturers in the pharmaceutical and nanotechnology sectors who require precise linker chemistry. The compound's dual functionality enables robust anchoring and flexible spacing in complex molecular assemblies.

Application

• Bioconjugation Linker: Used to covalently attach drugs, peptides, or imaging agents to nanoparticles, surfaces, or other biomolecules via the phosphonic acid group.
• Surface Functionalization: Key for modifying metal oxide surfaces (e.g., titanium, iron oxide) in medical devices, biosensors, and diagnostic platforms to improve biocompatibility and introduce specific functional groups.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of targeted drug delivery systems and antibody-drug conjugates (ADCs).
• Material Science: Employed in the development of self-assembled monolayers (SAMs) and hybrid organic-inorganic materials for controlled release and catalysis.
• Chelating Agent Precursor: The phosphonic acid moiety can be utilized to develop novel chelating agents for metal ion binding in separation technologies.

Basic Information

Product Name	m-Peg4-Phosphonic Acid
CAS No.	1872433-62-9
Molecular Formula	C11H25O9P
Molecular Weight	332.29 g/mol
Synonyms	4,7,10,13-Tetraoxa-16-phosphohexadecanoic acid; 15-Phosphonopentadeca-3,6,9,12-tetraoxaoic acid; (15-Carboxy-3,6,9,12-tetraoxapentadecyl)phosphonic acid; mPEG4-phosphonic acid; Amino-PEG4-phosphonic acid derivative; Phosphono-PEG4-acid; HOOC-PEG4-PO(OH)2; PEG4-based phosphonate linker
EINECS	Contact for details

Quality Control

Our m-Peg4-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere after each use to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.