Description

1-(4-Fluorophenyl)Butan-1-Amine Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the fluorophenyl moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	1-(4-Fluorophenyl)Butan-1-Amine Hydrochloride
CAS No.	1864055-90-2
Molecular Formula	C10H15ClFN
Molecular Weight	203.68 g/mol
Synonyms	1-(4-Fluorophenyl)butan-1-amine hydrochloride; 4-Fluoro-α-propylbenzylamine hydrochloride; (4-Fluorophenyl)butylamine hydrochloride; 1-Amino-1-(4-fluorophenyl)butane hydrochloride; 1-Butylamine, 1-(4-fluorophenyl)-, hydrochloride; 1-(p-Fluorophenyl)butylamine hydrochloride; 4-Fluoro-α-propylbenzenemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Butan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.