Description

6,8-Difluoro-2-Methylquinolin-4(1H)-One is a high-value, fluorinated quinolinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is essential for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique difluoro-methylquinolinone scaffold enables the introduction of specific bioactivity and metabolic stability. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for targeted synthesis and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, anti-infective, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a starting material for creating advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Employed in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions due to its specific fluorination pattern.
• Custom Synthesis & Contract Manufacturing: A vital substrate for fine chemical manufacturers offering bespoke synthesis and scale-up services for client projects.
• Academic & Institutional Research: Used in university and R&D laboratory settings for methodological development and exploring new chemical reactions involving fluorinated heterocycles.

Basic Information

Item	Details
Product Name	6,8-Difluoro-2-Methylquinolin-4(1H)-One
CAS No.	1862479-70-6
Molecular Formula	C₁₀H₇F₂NO
Molecular Weight	195.17 g/mol
Synonyms	6,8-Difluoro-2-methyl-1,4-dihydroquinolin-4-one; 6,8-Difluoro-2-methyl-4(1H)-quinolinone; 2-Methyl-6,8-difluoroquinolin-4(1H)-one; 4-Hydroxy-6,8-difluoro-2-methylquinoline; 6,8-Difluoro-2-methyl-4-quinolone; 1,4-Dihydro-6,8-difluoro-2-methyl-4-oxoquinoline
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-2-Methylquinolin-4(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.