Description

3-Bromo-6-(Methylsulfonyl)Quinoline is a high-purity, advanced pharmaceutical intermediate characterized by its brominated quinoline core and methylsulfonyl functional group. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule drugs targeting various disease pathways.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable bromine and sulfone moieties.
• Agrochemical Development: Serves as a building block for creating novel fungicides, herbicides, and insecticides with enhanced efficacy.
• Material Science: A potential monomer or additive in the development of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Biology Probes: Used to develop tool compounds and probes for studying biological processes and target validation.

Basic Information

Product Name	3-Bromo-6-(Methylsulfonyl)Quinoline
CAS No.	1860894-29-6
Molecular Formula	C₁₀H₈BrNO₂S
Molecular Weight	286.15 g/mol
Synonyms	6-(Methylsulfonyl)-3-bromoquinoline; 3-Bromo-6-methanesulfonylquinoline; Quinoline, 3-bromo-6-(methylsulfonyl)-; 1860894-29-6; 3-Bromo-6-(methylsulfonyl)quinoline; 3-Bromoquinoline-6-methyl sulfone
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Methylsulfonyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.