Description

6‐Fluoro‐5‐Nitro‐2,3‐Dihydro‐1H‐Indole is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and fluoro substituents for bioactivity.
• Material Science: Serves as a building block for creating specialty polymers, dyes, and organic electronic materials with tailored properties.
• Chemical Biology: Employed as a probe or linker in the design of chemical tools for studying enzyme function and cellular processes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	6‐Fluoro‐5‐Nitro‐2,3‐Dihydro‐1H‐Indole
CAS No.	1860028-18-7
Molecular Formula	C8H7FN2O2
Molecular Weight	182.15 g/mol
Synonyms	5-Nitro-6-fluoro-2,3-dihydro-1H-indole; 6-Fluoro-5-nitroindoline; 2,3-Dihydro-6-fluoro-5-nitro-1H-indole; 1H-Indole, 2,3-dihydro-6-fluoro-5-nitro-; 1860028-18-7; 6-Fluoro-5-nitroindoline; 5-Nitro-6-fluoroindoline
EINECS	Contact for details

Quality Control

Our 6‐Fluoro‐5‐Nitro‐2,3‐Dihydro‐1H‐Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.