Description

Glcnac Beta(1-2)Man α-1-Ethylazide is a synthetic, azide-functionalized carbohydrate derivative, specifically a disaccharide mimetic, with the CAS registry number 1858224-15-3. This compound is a crucial building block in chemical biology and glycochemistry, enabling the site-specific conjugation of complex oligosaccharides via bioorthogonal click chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and biotechnology sectors for developing novel glycoconjugate vaccines, targeted therapeutics, and advanced diagnostic probes.

Application

• Glycoconjugate Vaccine Development: Serves as a key intermediate for synthesizing well-defined, immunogenic carbohydrate antigens linked to carrier proteins.
• Antibody-Drug Conjugate (ADC) Payload Attachment: Enables the precise, chemoselective coupling of cytotoxic drugs to monoclonal antibodies via the reactive azide group.
• Cell Surface Engineering & Labeling: Used in metabolic glycan engineering to incorporate azide tags onto cell surfaces for subsequent imaging or capture using click chemistry.
• Synthesis of Glycan Arrays: A critical precursor for constructing high-density glycan microarrays to study protein-carbohydrate interactions.
• Biomaterial Functionalization: Facilitates the modification of hydrogels, nanoparticles, and other biomaterials with bioactive carbohydrate motifs.
• Pharmaceutical Intermediate: Acts as a sophisticated chiral synthon in the multi-step synthesis of complex glycosidase inhibitors or other carbohydrate-based drugs.

Basic Information

Product Name	Glcnac Beta(1-2)Man α-1-Ethylazide
CAS No.	1858224-15-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Ethylazide-α-Man-(1→?)-β-GlcNAc; N-Acetylglucosamine-β-(1-2)-mannose α-ethyl azide; Azidoethyl mannosyl-GlcNAc derivative; Click chemistry carbohydrate; Glycosyl azide building block; Synthetic disaccharide azide; Bioorthogonal conjugation reagent
EINECS	Contact for details

Quality Control

Our Glcnac Beta(1-2)Man α-1-Ethylazide is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC for purity, NMR (1H, 13C) for structural confirmation, and Mass Spectrometry (HRMS or ESI-MS) for molecular weight verification. Our quality commitment supports research and development requiring high-purity, well-defined chemical biology tools.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when possible to prevent decomposition. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.