Description

3-Nitro-5-(Trifluoromethyl)Pyridin-2-Ol is a high-value, multi-functional pyridine derivative that serves as a critical synthetic intermediate. Its unique structure, featuring both nitro and trifluoromethyl substituents, makes it an essential building block for creating advanced molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a building block for developing specialty chemicals, such as ligands for catalysis, organic electronic materials, and advanced polymers.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, enzyme inhibitors, and tool compounds in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Nitro-5-(Trifluoromethyl)Pyridin-2-Ol
CAS No.	1851650-55-9
Molecular Formula	C6H3F3N2O3
Molecular Weight	208.10 g/mol
Synonyms	2-Hydroxy-3-nitro-5-(trifluoromethyl)pyridine; 3-Nitro-5-(trifluoromethyl)-2-pyridinol; 3-Nitro-5-(trifluoromethyl)pyridin-2(1H)-one; 5-(Trifluoromethyl)-3-nitropyridin-2-ol; 2-Pyridinol, 3-nitro-5-(trifluoromethyl)-; 1851650-55-9
EINECS	Contact for details

Quality Control

Every batch of 3-Nitro-5-(Trifluoromethyl)Pyridin-2-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.