Description

6'-Bromo-8'-Methyl-1'H-Spiro[Cyclohexane-1,3'-Imidazo[1,5-A]Pyridine]-1',5'(2'H)-Dione is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and fused heterocyclic architecture. This compound matters as a critical building block for medicinal chemistry research, enabling the synthesis of novel drug candidates with potential activity in central nervous system (CNS) and other therapeutic areas. It is primarily needed by R&D organizations, pharmaceutical companies, and CROs engaged in the development of new chemical entities, particularly those exploring imidazopyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Explored for the synthesis of potential therapeutics targeting neurological disorders, given the imidazopyridine moiety's relevance in this field.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by fine chemical manufacturers for the contract synthesis of complex molecules for client-specific projects.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6'-Bromo-8'-Methyl-1'H-Spiro[Cyclohexane-1,3'-Imidazo[1,5-A]Pyridine]-1',5'(2'H)-Dione
CAS No.	1849592-70-6
Molecular Formula	C14H15BrN2O2
Molecular Weight	323.19 g/mol
Synonyms	6'-Bromo-8'-methyl-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'(2'H)-dione; Spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione, 6'-bromo-8'-methyl-1'H,2'H-; 1'H-Spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'(2'H)-dione, 6'-bromo-8'-methyl-; 1849592-70-6; 6-Bromo-8-methyl-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione
EINECS	Contact for details

Quality Control

Our 6'-Bromo-8'-Methyl-1'H-Spiro[Cyclohexane-1,3'-Imidazo[1,5-A]Pyridine]-1',5'(2'H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support development and commercial projects with custom purity grades to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be handled as moisture-sensitive. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.