Description

3-Bromo-6,7-Difluoroquinoline is a high-value, multi-functional halogenated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity building block for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, and pesticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials due to its fluorinated aromatic structure.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the quinoline moiety into more complex molecules.
• Ligand & Catalyst Development: Utilized for creating novel nitrogen-containing ligands for transition metal catalysis.
• Academic & Industrial R&D: A fundamental reagent for exploring new chemical spaces and reaction methodologies in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	3-Bromo-6,7-Difluoroquinoline
CAS No.	1841081-70-6
Molecular Formula	C9H4BrF2N
Molecular Weight	244.04 g/mol
Synonyms	3-Bromo-6,7-difluoroquinoline; 6,7-Difluoro-3-bromoquinoline; Quinoline, 3-bromo-6,7-difluoro-; 1841081-70-6
EINECS	Contact for details

Quality Control

Our 3-Bromo-6,7-Difluoroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.