Description

1-Fluoro-5,7-Dioxa-6-Thiaspiro[2.5]Octane 6-Oxide is a specialized spirocyclic heterocyclic compound featuring a unique fluorine-containing oxathiolane dioxide structure, serving as a high-value synthetic intermediate. This compound is engineered to provide a reactive fluorinated building block, enabling the precise introduction of functional groups into complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and novel polymer synthesis.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon for the development of new active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent for developing specialty polymers with tailored surface properties or specific reactivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel fluorinated ligands for catalysis and asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research focused on exploring new fluorination methodologies and reaction mechanisms.
• Diagnostic Agent Synthesis: Potential use in the construction of fluorinated probes or contrast agents for medical imaging techniques like PET (Positron Emission Tomography).

Basic Information

Product Name	1-Fluoro-5,7-Dioxa-6-Thiaspiro[2.5]Octane 6-Oxide
CAS No.	1835276-52-2
Molecular Formula	C5H7FO3S
Molecular Weight	166.17 g/mol
Synonyms	1-Fluoro-5,7-dioxa-6-thiaspiro[2.5]octane 6-oxide; 6-Oxido-1-fluoro-5,7-dioxa-6-thiaspiro[2.5]octane; 1-Fluoro-5,7-dioxa-6-thiaspiro[2.5]octane-6-oxide; Fluorinated oxathiolane dioxide; Spiro[2.5]octane, 1-fluoro-5,7-dioxa-6-thia-, 6-oxide
EINECS	Contact for details

Quality Control

Our 1-Fluoro-5,7-Dioxa-6-Thiaspiro[2.5]Octane 6-Oxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should be kept sealed and only opened in an inert environment. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.