Description

3-Fluorobicyclo[1.1.1]pentan-1-amine hydrochloride (Wx120752S1) is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the design of novel bioactive molecules and PROTACs (Proteolysis Targeting Chimeras). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of next-generation therapeutics targeting the central nervous system and other disease areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those requiring a rigid, three-dimensional fluorine-containing amine moiety.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to modulate pharmacokinetic properties like metabolic stability and membrane permeability.
• PROTAC Linker Component: Incorporated into bifunctional molecules designed to degrade target proteins, leveraging its amine group for conjugation.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents with enhanced activity.
• Material Science: Potential monomer or cross-linking agent for creating specialty polymers with unique physical properties.
• Chemical Biology Probes: Used to create labeled compounds for studying biological processes and target engagement.

Basic Information

Product Name	3-Fluorobicyclo[1.1.1]pentan-1-amine hydrochloride (Wx120752S1)
CAS No.	1826900-79-1
Molecular Formula	C5H9ClFN
Molecular Weight	137.58 g/mol
Synonyms	3-Fluorobicyclo[1.1.1]pentan-1-amine HCl; 1-Amino-3-fluorobicyclo[1.1.1]pentane hydrochloride; 3-Fluoro-1-aminobicyclo[1.1.1]pentane hydrochloride; 3-Fluoro-BCP-NH2·HCl; 3-F-BCP-amine hydrochloride; Wx120752S1; 1826900-79-1; 3-Fluoropentacyclo[1.1.1.0¹,³.0²,⁴.0³,⁵]pentan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Fluorobicyclo[1.1.1]pentan-1-amine hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.