Description

4-Chloroquinolin-5-Amine is a high-purity, halogenated quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific chloroquinoline motifs into their target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactive quinoline core.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), and advanced polymers.
• Chemical Biology & Proteomics: Employed as a tagging reagent or a scaffold for designing chemical probes to study biological pathways and protein functions.
• Academic & Contract Research: Fundamental building block for methodological studies in organic chemistry and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	4-Chloroquinolin-5-Amine
CAS No.	1824318-74-2
Molecular Formula	C9H7ClN2
Molecular Weight	178.62 g/mol
Synonyms	5-Amino-4-chloroquinoline; 4-Chloro-5-quinolinamine; 4-Chloroquinolin-5-ylamine; Quinoline, 5-amino-4-chloro-; 5-Amino-4-chloro-quinoline; 4-Chloro-5-aminoquinoline; 1824318-74-2
EINECS	Contact for details

Quality Control

Our 4-Chloroquinolin-5-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as verified by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.