Description

3-(Trifluoromethyl)Quinolin-5-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline scaffold substituted with a trifluoromethyl group and an amine functionality. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new drugs, crop protection agents, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in oncology, neurology, and anti-infective research.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in organic chemistry research for constructing complex heterocyclic compounds via its reactive amine group.
• Fluorine Chemistry Studies: Acts as a valuable substrate for investigating the effects of fluorine substitution on chemical and physical properties.

Basic Information

Product Name	3-(Trifluoromethyl)Quinolin-5-Amine
CAS No.	1824276-05-2
Molecular Formula	C₁₀H₇F₃N₂
Molecular Weight	212.17 g/mol
Synonyms	5-Amino-3-(trifluoromethyl)quinoline; 3-Trifluoromethyl-5-aminoquinoline; Quinolin-5-amine, 3-(trifluoromethyl)-; 5-Quinolinamine, 3-(trifluoromethyl)-; 1824276-05-2; 3-(Trifluoromethyl)-5-quinolinamine; 5-Amino-3-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.