Description

4-Chloro-1H-Imidazole-2-Carboxylic Acid is a high-value halogenated imidazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and a chloro substituent on the imidazole core, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that incorporate halogenated heterocycles for enhanced activity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Building block for advanced polymers and organic electronic materials requiring functionalized heteroaromatic units.
• Chemical Biology: Useful for synthesizing probes and molecular tools to study biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4-Chloro-1H-Imidazole-2-Carboxylic Acid
CAS No.	1824084-44-7
Molecular Formula	C4H3ClN2O2
Molecular Weight	146.53 g/mol
Synonyms	4-Chloro-1H-imidazole-2-carboxylic acid; 2-Carboxy-4-chloroimidazole; 4-Chloroimidazole-2-carboxylic Acid; 1H-Imidazole-2-carboxylic acid, 4-chloro-; 4-Chloro-2-imidazolecarboxylic Acid; 4-Chloro-2-carboxyimidazole; 4-Chloroimidazole-2-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Chloro-1H-Imidazole-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.