Description

5-Bromo-2-Methylquinazolin-4(3H)-One is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for lead optimization and scale-up development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small molecule drug candidates.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead compound optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides and fungicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	5-Bromo-2-Methylquinazolin-4(3H)-One
CAS No.	1823954-54-6
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	5-Bromo-2-methyl-3,4-dihydroquinazolin-4-one; 5-Bromo-2-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 5-bromo-2-methyl-; 5-Bromo-2-methylquinazolin-4-ol; 1823954-54-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methylquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.