Description

5-Fluoroquinoline-8-Carbonitrile is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a versatile scaffold for introducing both fluorine and nitrile functional groups. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science: Acts as a building block for creating functionalized organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Synthesis: Provides a versatile platform for further derivatization via reactions at the nitrile group or the quinoline ring system for library synthesis in discovery chemistry.

Basic Information

Product Name	5-Fluoroquinoline-8-Carbonitrile
CAS No.	1823944-97-3
Molecular Formula	C10H5FN2
Molecular Weight	172.16 g/mol
Synonyms	8-Cyano-5-fluoroquinoline; 5-Fluoro-8-quinolinecarbonitrile; Quinoline-8-carbonitrile, 5-fluoro-; 5-Fluoroquinoline-8-carbonitrile; 1823944-97-3; 5-Fluoro-8-cyanoquinoline; 8-CN-5-F-quinoline
EINECS	Contact for details

Quality Control

Our 5-Fluoroquinoline-8-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.