Description

5,7-Difluoroquinazolin-2-Amine is a high-purity, fluorinated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Chemical Research: Used as a specialized scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Material Science: Investigated for the development of advanced organic electronic materials due to its fluorinated quinazoline core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Item	Detail
Product Name	5,7-Difluoroquinazolin-2-Amine
CAS No.	1823913-89-8
Molecular Formula	C8H5F2N3
Molecular Weight	181.14 g/mol
Synonyms	2-Amino-5,7-difluoroquinazoline; 5,7-Difluoro-2-quinazolinamine; 5,7-Difluoroquinazolin-2-ylamine; 2-Quinazolinamine, 5,7-difluoro-; 1823913-89-8
EINECS	Contact for details

Quality Control

Our 5,7-Difluoroquinazolin-2-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides, as indicated by its chemical properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.