Description

4,4,5-Trifluoroazepane Hydrochloride (Wx601138) is a high-purity fluorinated azepane derivative, offered as a hydrochloride salt for enhanced stability and handling. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the creation of novel fluorinated pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced materials with unique surface properties.
• Chemical Biology Probes: Useful for incorporating fluorine atoms into molecular probes for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring a fluorinated heterocyclic scaffold.

Basic Information

Product Name	4,4,5-Trifluoroazepane Hydrochloride (Wx601138)
CAS No.	1823871-41-5
Molecular Formula	C6H10F3N•HCl
Molecular Weight	189.61 g/mol
Synonyms	4,4,5-Trifluoroazepane HCl; 1-Aza-4,4,5-trifluorocycloheptane Hydrochloride; Heptafluoroazepane Hydrochloride (common misnomer); WX-601138; 4,4,5-Trifluorohexamethyleneimine Hydrochloride; 4,4,5-Trifluoroperhydroazepine Hydrochloride; Azepane, 4,4,5-trifluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4,4,5-Trifluoroazepane Hydrochloride is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.