Description

1-Oxaspiro[3.5]Nonan-7-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic oxa-ketone structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with specific stereochemical and functional properties.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex spirocyclic scaffolds found in potential drug candidates targeting CNS disorders, metabolic diseases, and infectious diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve pharmacokinetic properties.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, or insecticides with new modes of action.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique thermal or mechanical properties.
• Catalyst & Ligand Development: The oxygen and carbonyl functionalities make it a candidate for designing novel chiral ligands or organocatalysts for asymmetric synthesis.
• Academic & Contract Research: Supplied to universities and CROs for fundamental organic synthesis research and custom synthesis projects.

Basic Information

Product Name	1-Oxaspiro[3.5]Nonan-7-One
CAS No.	1823366-07-9
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	1-Oxaspiro[3.5]nonan-7-one; 7-Oxaspiro[3.5]nonan-1-one; Spiro[3.5]nonane-7-one, 1-oxa-; Oxaspiro[3.5]nonan-7-one; 1823366-07-9; 1-Oxa-spiro[3.5]nonan-7-one; 7-Oxa-spiro[3.5]nonan-1-one
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[3.5]Nonan-7-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases, strong reducing agents, and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.