Description

2-tert-Butyl 8-Ethyl 6-Benzyl-2,6-Diazaspiro[3.4]Octane-2,8-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel bioactive molecules. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in the discovery of new therapeutic agents, particularly in areas targeting central nervous system (CNS) disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of heterobifunctional degraders.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for research purposes.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	2-tert-Butyl 8-Ethyl 6-Benzyl-2,6-Diazaspiro[3.4]Octane-2,8-Dicarboxylate
CAS No.	1823261-82-0
Molecular Formula	C22H32N2O4
Molecular Weight	388.50 g/mol
Synonyms	2,6-Diazaspiro[3.4]octane-2,8-dicarboxylic acid, 6-(phenylmethyl)-, 2-(1,1-dimethylethyl) 8-ethyl ester; 2-(tert-Butyl) 8-ethyl 6-benzyl-2,6-diazaspiro[3.4]octane-2,8-dicarboxylate; 6-Benzyl-2-(tert-butoxycarbonyl)-8-(ethoxycarbonyl)-2,6-diazaspiro[3.4]octane; tert-Butyl 8-ethyl 6-benzyl-2,6-diazaspiro[3.4]octane-2,8-dicarboxylate; BOC-Diazaspirooctane-ethyl ester; CAS 1823261-82-0; Spirocyclic diaza building block
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 8-Ethyl 6-Benzyl-2,6-Diazaspiro[3.4]Octane-2,8-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.