Description

3-Chloroquinoline-5-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals, where its unique chlorinated quinoline scaffold enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating novel compounds with targeted biological or functional properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a versatile backbone for creating complex ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, fluorescent dyes, and other functional materials.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex quinoline derivatives.

Basic Information

Product Name	3-Chloroquinoline-5-Carboxylic Acid
CAS No.	1823254-06-3
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Quinolinecarboxylic acid, 3-chloro-; 3-Chloro-5-quinolinecarboxylic acid; 3-Chloroquinoline-5-carboxylic acid; Quinoline-5-carboxylic acid, 3-chloro derivative; 1823254-06-3; 3-Chloro-quinoline-5-carboxylic acid; 3-Cl-quinoline-5-COOH
EINECS	Contact for details

Quality Control

Our 3-Chloroquinoline-5-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.