Description

trans-N1,N1-Dimethylcyclobutane-1,3-Diamine is a high-purity, specialized diamine building block featuring a constrained cyclobutane ring structure. This compound is valued for its unique stereochemistry and dual amine functionality, which are critical for synthesizing complex molecules with specific spatial and electronic properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as catalyst development, chiral ligand synthesis, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for creating constrained peptide mimetics and bioactive molecules.
• Catalyst & Ligand Synthesis: Used to develop sophisticated chiral ligands and organocatalysts for asymmetric synthesis, enhancing reaction selectivity and yield.
• Agrochemical Research: Employed in the design and synthesis of new herbicides, fungicides, and plant growth regulators with improved efficacy.
• Polymer Modification: Acts as a curing agent or cross-linker in specialty epoxy and polyurethane systems, imparting rigidity and thermal stability.
• Chemical Research & Development: A versatile reagent for exploring new reaction pathways and constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	trans-N1,N1-Dimethylcyclobutane-1,3-Diamine
CAS No.	1821832-50-1
Molecular Formula	C7H16N2
Molecular Weight	128.22 g/mol
Synonyms	trans-1,3-Bis(dimethylamino)cyclobutane; (1r,3r)-N1,N1,N3,N3-Tetramethylcyclobutane-1,3-diamine; trans-N,N,N',N'-Tetramethylcyclobutane-1,3-diamine; trans-TMCDA; 1,3-Cyclobutanediamine, N1,N1,N3,N3-tetramethyl-, (1r,3r)-; trans-1,3-Diamino-N,N,N',N'-tetramethylcyclobutane
EINECS	Contact for details

Quality Control

Our trans-N1,N1-Dimethylcyclobutane-1,3-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high chemical purity and consistent isomeric composition. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.