Description

6-Methoxy-1,2,3,4-Tetrahydro-1,8-Naphthyridine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates.
• Drug Discovery Scaffold: Used in medicinal chemistry for constructing libraries of compounds targeting specific biological pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the final synthetic steps for producing complex therapeutic molecules.
• Biochemical Research: Employed as a standard or reagent in studies investigating enzyme inhibition or receptor binding.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes from laboratory to pilot and commercial production scales.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations for cGMP production.

Basic Information

Product Name	6-Methoxy-1,2,3,4-Tetrahydro-1,8-Naphthyridine
CAS No.	1820735-64-5
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	6-Methoxy-1,2,3,4-tetrahydro-1,8-naphthyridine; 1,2,3,4-Tetrahydro-6-methoxy-1,8-naphthyridine; 6-Methoxy-1,8-naphthyridine, 1,2,3,4-tetrahydro-; 1,8-Naphthyridine, 1,2,3,4-tetrahydro-6-methoxy-; 1820735-64-5; 6-Methoxy-1,2,3,4-tetrahydro-[1,8]naphthyridine
EINECS	Contact for details

Quality Control

Our 6-Methoxy-1,2,3,4-Tetrahydro-1,8-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.