Description

8-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1820735-63-4. This compound is a critical building block in modern medicinal chemistry, valued for its unique heterocyclic scaffold that enables the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery: Integral to the synthesis of potential therapeutic agents targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	8-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine
CAS No.	1820735-63-4
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	8-Methoxy-1,2,3,4-tetrahydro-1,6-naphthyridine; 1,2,3,4-Tetrahydro-8-methoxy-1,6-naphthyridine; 1,6-Naphthyridine, 1,2,3,4-tetrahydro-8-methoxy-; 1820735-63-4; 8-Methoxy-1,6-naphthyridine, 1,2,3,4-tetrahydro-; Tetrahydro-8-methoxy-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.