Description

1-(2-Fluoropyridin-4-Yl)Piperazine Dihydrochloride is a high-purity fluorinated piperazine derivative, serving as a critical building block in modern pharmaceutical research and development. Its molecular structure, featuring a fluoropyridine moiety, is engineered to enhance the metabolic stability and binding affinity of potential drug candidates. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new chemical entities (NCEs), particularly in central nervous system (CNS) and oncology research programs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and herbicides, leveraging the fluorine atom for improved bioactivity.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and receptor interactions.
• Process Chemistry & Scale-Up: Serves as a reliable starting material for the optimization and kilogram-scale production of target molecules.
• Library Synthesis for High-Throughput Screening (HTS): An essential component for generating diverse compound libraries to identify new lead structures.

Basic Information

Product Name	1-(2-Fluoropyridin-4-Yl)Piperazine Dihydrochloride
CAS No.	1820711-96-3
Molecular Formula	C9H13Cl2FN4
Molecular Weight	267.13 g/mol
Synonyms	1-(2-Fluoropyridin-4-yl)piperazine dihydrochloride; 4-(2-Fluoropyridin-4-yl)piperazine dihydrochloride; 2-Fluoro-4-(piperazin-1-yl)pyridine dihydrochloride; 1-(2-Fluoro-4-pyridinyl)piperazine dihydrochloride; Piperazine, 1-(2-fluoro-4-pyridinyl)-, dihydrochloride; 1820711-96-3; FC-1342 (Potential Research Code)
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Fluoropyridin-4-Yl)Piperazine Dihydrochloride is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.