Description

8-Bromo-5-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine is a high-purity, advanced pharmaceutical intermediate with a unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for potential APIs.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-5-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine
CAS No.	1820711-91-8
Molecular Formula	C9H11BrN2O
Molecular Weight	243.10 g/mol
Synonyms	8-Bromo-5-methoxy-1,2,3,4-tetrahydro-1,6-naphthyridine; 1,2,3,4-Tetrahydro-8-bromo-5-methoxy-1,6-naphthyridine; 5-Methoxy-8-bromo-1,2,3,4-tetrahydro-1,6-naphthyridine; 1820711-91-8; 8-Bromo-5-methoxy-1,6-naphthyridine, 1,2,3,4-tetrahydro-; SCHEMBL24245419; AKOS040759232; ZINC000000000000
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Methoxy-1,2,3,4-Tetrahydro-1,6-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.