Description

3-Iodo-4-Oxo-1,4-Dihydro-Quinoline-6-Carbonitrile is a high-purity, functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinoline scaffold is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs or conductive polymers.
• Chemical Synthesis: Acts as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine substituent.
• Ligand and Catalyst Development: Utilized for constructing complex chelating ligands for metal catalysts used in asymmetric synthesis.
• Fluorescent Probe Synthesis: The quinoline core can be modified to create dyes and molecular probes for biochemical sensing and imaging.

Basic Information

Item	Detail
Product Name	3-Iodo-4-Oxo-1,4-Dihydro-Quinoline-6-Carbonitrile
CAS No.	1820708-03-9
Molecular Formula	C10H5IN2O
Molecular Weight	296.06 g/mol
Synonyms	6-Cyano-3-iodo-1,4-dihydro-4-oxoquinoline; 3-Iodo-1,4-dihydro-4-oxoquinoline-6-carbonitrile; 3-Iodo-4-oxo-1,4-dihydroquinoline-6-carbonitrile; Quinoline-6-carbonitrile, 1,4-dihydro-3-iodo-4-oxo-; 1820708-03-9; 3-Iodo-4-oxoquinoline-6-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-4-Oxo-1,4-Dihydro-Quinoline-6-Carbonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.