Description

3-Bromo-2-Chloro-4-Methyl-1,5-Naphthyridine is a high-purity, multi-halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogen-substituted structure makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the naphthyridine core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to its reactive bromo and chloro substituents.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and coordination chemistry.

Basic Information

Product Name	3-Bromo-2-Chloro-4-Methyl-1,5-Naphthyridine
CAS No.	1820704-12-8
Molecular Formula	C9H6BrClN2
Molecular Weight	257.51 g/mol
Synonyms	3-Bromo-2-chloro-4-methyl-1,5-naphthyridine; 1,5-Naphthyridine, 3-bromo-2-chloro-4-methyl-; 1820704-12-8; 4-Methyl-3-bromo-2-chloro-1,5-naphthyridine; 2-Chloro-3-bromo-4-methyl-1,5-naphthyridine; 3-Bromo-2-chloro-4-methyl-[1,5]naphthyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-4-Methyl-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.