Description

Methyl 2-(4-Amino-2-Fluorophenyl)Acetate Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step production of complex APIs requiring a fluorinated aniline derivative.
• Chemical Research & Development: Serves as a versatile precursor for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of pharmaceutical compounds under GMP conditions.
• Reference Standard: Used as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Methyl 2-(4-Amino-2-Fluorophenyl)Acetate Hydrochloride
CAS No.	1820686-43-8
Molecular Formula	C9H11FNO2 • HCl
Molecular Weight	219.65 (Free base) / 256.11 (HCl salt)
Synonyms	2-Fluoro-4-aminophenylacetic acid methyl ester hydrochloride; Methyl (4-amino-2-fluorophenyl)acetate hydrochloride; 4-Amino-2-fluorophenylacetic acid methyl ester HCl; 2-(4-Amino-2-fluorophenyl)acetic acid methyl ester hydrochloride; Methyl 2-(4-amino-2-fluorophenyl)ethanoate hydrochloride; (4-Amino-2-fluorophenyl)acetic acid methyl ester hydrochloride; Methyl α-(4-amino-2-fluorophenyl)acetate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 2-(4-Amino-2-Fluorophenyl)Acetate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.