Description

6-Bromo-7-Cyano Quinoline is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, which combines a bromo-substituent for cross-coupling reactions with a cyano group for further functionalization, enabling the rapid construction of complex molecules. It is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct advanced quinoline-based fungicides, herbicides, and plant growth regulators.
• Material Science Building Block: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Cross-Coupling Reactions: The bromine atom serves as an excellent handle for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Cyanide Group Transformation: The cyano functionality can be hydrolyzed to carboxylic acids or reduced to amines, enabling diverse molecular pathways.
• Ligand and Catalyst Development: Acts as a scaffold for creating novel chelating ligands in coordination chemistry and catalysis.

Basic Information

Item	Details
Product Name	6-Bromo-7-Cyano Quinoline
CAS No.	1820674-85-8
Molecular Formula	C10H5BrN2
Molecular Weight	233.07 g/mol
Synonyms	6-Bromo-7-cyanoquinoline; 7-Cyano-6-bromoquinoline; Quinoline, 6-bromo-7-cyano-; 6-Bromo-quinoline-7-carbonitrile; 6-Bromo-7-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-7-Cyano Quinoline is produced under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our commitment to consistent quality and supply chain reliability supports your critical development timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.