Description

Indoline-6-Carbohydrazide Dihydrochloride is a high-purity, dihydrochloride salt derivative of indoline carbohydrazide, serving as a critical advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents, including potential kinase inhibitors and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Bioconjugation & Probe Development: The carbohydrazide moiety can be utilized for conjugation with aldehydes or ketones in the development of biochemical probes.
• Chemical Synthesis: Serves as a precursor for the preparation of more complex heterocyclic compounds and fused ring systems.
• Academic & Industrial R&D: Employed in research laboratories for exploring new synthetic pathways and chemical biology applications.

Basic Information

Product Name	Indoline-6-Carbohydrazide Dihydrochloride
CAS No.	1820651-33-9
Molecular Formula	C9H12Cl2N4O
Molecular Weight	263.12 g/mol
Synonyms	1H-Indole-6-carbohydrazide dihydrochloride; Indoline-6-carboxylic acid hydrazide dihydrochloride; 2,3-Dihydro-1H-indole-6-carbohydrazide dihydrochloride; 6-Hydrazinylcarbonylindoline dihydrochloride; 1H-Indole-6-carboxylic acid, hydrazide, dihydrochloride; 2,3-Dihydro-1H-indole-6-carboxylic acid hydrazide dihydrochloride; (2,3-Dihydro-1H-indol-6-yl)formohydrazide dihydrochloride
EINECS	Contact for details

Quality Control

Our Indoline-6-Carbohydrazide Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and opened under dry, inert conditions when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.