Description

3-(Trifluoromethyl)Quinolin-4-Amine CAS NO 1820650-23-4 is a high-purity, advanced pharmaceutical intermediate characterized by its quinoline core and trifluoromethyl functional group. This compound is essential for medicinal chemistry research and development, offering a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science: Serves as a precursor for the development of advanced organic electronic materials and fluorescent dyes.
• Chemical Synthesis: Employed in organic synthesis as a versatile amine-containing heterocycle for constructing more complex molecular architectures.
• Bioconjugation & Probe Development: Useful for creating chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Product Name	3-(Trifluoromethyl)Quinolin-4-Amine
CAS No.	1820650-23-4
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	4-Amino-3-(trifluoromethyl)quinoline; 3-Trifluoromethyl-4-quinolinamine; 4-Quinolinamine, 3-(trifluoromethyl)-; Quinolin-4-amine, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)-4-aminoquinoline; 3-Trifluoromethylquinolin-4-ylamine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.