Description

2-[(tert-Butylsulfanyl)Methyl]Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfur-containing piperidine scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting neurological and metabolic pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its tert-butylthio and piperidine motifs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for preclinical and clinical trial material production.
• Ligand and Catalyst Precursor: Potential use in the development of novel ligands for asymmetric catalysis or metal complexes.
• Chemical Biology Probes: Can be incorporated into molecular probes for studying enzyme function or protein interactions.
• Custom Synthesis: Foundation for the bespoke manufacturing of specialized fine chemicals and reference standards.

Basic Information

Product Name	2-[(tert-Butylsulfanyl)Methyl]Piperidine Hydrochloride
CAS No.	1820639-50-6
Molecular Formula	C10H22ClNS
Molecular Weight	223.81 g/mol
Synonyms	2-[(tert-Butylthio)methyl]piperidine hydrochloride; 2-[(tert-Butylsulfanyl)methyl]piperidine HCl; 2-[(tert-Butylmercapto)methyl]piperidine hydrochloride; Piperidine, 2-[(1,1-dimethylethyl)thio]methyl]-, hydrochloride (1:1); 2-((tert-Butylthio)methyl)piperidine hydrochloride; 1820639-50-6; tert-Butyl 2-piperidinylmethyl sulfide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[(tert-Butylsulfanyl)Methyl]Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, guaranteeing compliance with your research and development specifications. Our commitment to quality assurance supports reliable and reproducible results in your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.