Description

2-Bromo-5-Iodophenyl Methyl Sulphone is a high-purity, multi-halogenated aromatic sulphone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on the phenyl ring, makes it a versatile intermediate for constructing complex molecules through selective cross-coupling reactions. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring selective Suzuki-Miyaura or other palladium-catalyzed cross-couplings.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the halogenated phenyl sulphone moiety can impart specific biological activity.
• Material Science: Serves as a building block for creating advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing sulphone group and halogen handles.
• Chemical Synthesis: Employed in medicinal and process chemistry for the late-stage functionalization of complex molecules, enabling rapid exploration of structure-activity relationships (SAR).
• Ligand & Catalyst Development: Useful in the preparation of specialized ligands or organocatalysts where the sulphone group can influence metal coordination or catalytic activity.

Basic Information

Product Name	2-Bromo-5-Iodophenyl Methyl Sulphone
CAS No.	1820619-59-7
Molecular Formula	C7H6BrIO2S
Molecular Weight	360.99 g/mol
Synonyms	1-Bromo-2-(methylsulfonyl)-4-iodobenzene; (2-Bromo-5-iodophenyl)(methyl)sulfone; Methyl 2-bromo-5-iodophenyl sulphone; 2-Bromo-5-iodobenzene methyl sulphone; 4-Iodo-2-bromophenyl methyl sulfone; 2-Bromo-5-iodophenyl methyl sulfone; 2-Bromo-5-iodophenylmethylsulfone
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodophenyl Methyl Sulphone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.