Description

1-(Ethanesulfonyl)-4-Nitro-2-(Trifluoromethyl)Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and nitro-substituted benzene core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or receptor modulation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for specialty polymers or liquid crystals, leveraging its electron-withdrawing groups to tune material properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized aryl groups into more complex architectures.
• Chemical Biology: Utilized as a probe or linker in the development of chemical tools for studying biological pathways.

Basic Information

Product Name	1-(Ethanesulfonyl)-4-Nitro-2-(Trifluoromethyl)Benzene
CAS No.	1820615-46-0
Molecular Formula	C9H8F3NO4S
Molecular Weight	283.22 g/mol
Synonyms	4-Nitro-2-(trifluoromethyl)-1-(ethylsulfonyl)benzene; 1-Ethanesulfonyl-4-nitro-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)-4-nitrobenzenesulfonylethane; Benzene, 1-(ethanesulfonyl)-4-nitro-2-(trifluoromethyl)-; 4-Nitro-α,α,α-trifluoro-2-(ethylsulfonyl)toluene
EINECS	Contact for details

Quality Control

Our 1-(Ethanesulfonyl)-4-Nitro-2-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.