Description

(1R)-1-(3-Fluoro-4-Methylphenyl)Ethylamine Hydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical synthesis and fine chemical research. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), particularly where stereochemistry is a key factor for biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a specific chiral center into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands for metal-catalyzed asymmetric transformations.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(1R)-1-(3-Fluoro-4-Methylphenyl)Ethylamine Hydrochloride
CAS No.	1820570-24-8
Molecular Formula	C9H13ClFN
Molecular Weight	189.66 g/mol
Synonyms	(1R)-1-(3-Fluoro-4-methylphenyl)ethan-1-amine hydrochloride; (R)-1-(3-Fluoro-4-methylphenyl)ethylamine HCl; (R)-α-Methyl-3-fluoro-4-methylbenzylamine hydrochloride; (R)-1-(3-Fluoro-p-tolyl)ethylamine hydrochloride; (R)-3-Fluoro-4-methyl-α-methylbenzylamine hydrochloride; (R)-1-(3-Fluoro-4-methylphenyl)ethanamine hydrochloride; Benzenemethanamine, 3-fluoro-α-methyl-4-methyl-, hydrochloride, (αR)-
EINECS	Contact for details

Quality Control

Our (1R)-1-(3-Fluoro-4-Methylphenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.