Description

Bicyclo[2.2.1]Heptane-1,4-Diamine Dihydrochloride is a high-purity, specialty diamine salt with a rigid norbornane backbone, offering a unique combination of structural rigidity and dual amine functionality. This compound is a critical chiral building block and ligand precursor in advanced pharmaceutical synthesis and asymmetric catalysis. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold for the synthesis of complex drug candidates, particularly in neurology and oncology research.
• Asymmetric Catalyst Ligand: Used as a precursor for developing novel chiral ligands in transition metal catalysis for enantioselective synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing high-performance polyamides, polyimides, and epoxy resins with enhanced thermal stability.
• Agrochemical Synthesis: Employed in the research and development of new herbicides and pesticides with specific stereochemical requirements.
• Chelating Agent: Functions as a chelator for metal ions in analytical chemistry and material coating applications.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within university and corporate laboratories.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1,4-Diamine Dihydrochloride
CAS No.	1818847-46-9
Molecular Formula	C7H14N2·2HCl
Molecular Weight	207.11 g/mol
Synonyms	1,4-Diaminonorbornane Dihydrochloride; Norbornane-1,4-diamine Dihydrochloride; endo,exo-Bicyclo[2.2.1]heptane-1,4-diamine Dihydrochloride; 1,4-Diaminobicyclo[2.2.1]heptane Dihydrochloride; (1R,4R)-Bicyclo[2.2.1]heptane-1,4-diamine Dihydrochloride; (1S,4S)-Bicyclo[2.2.1]heptane-1,4-diamine Dihydrochloride; Bicyclo[2.2.1]heptane-1,4-diyldiamine Dihydrochloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-1,4-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing specific batch results are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specific isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.