Description

Tetrakis[n-Tetrachlorophthaloyl-(S)-tert-Leucinato]Dirhodium Bis(Ethyl Acetate) Adduct is a highly specialized, chiral dirhodium(II) carboxylate complex designed for asymmetric catalysis. This compound matters for its ability to facilitate highly enantioselective C–H functionalization and cyclopropanation reactions, enabling the synthesis of complex chiral molecules with precise stereocontrol. It is essential for research chemists and process development scientists in the pharmaceutical and fine chemical industries who require robust, high-performance catalysts for constructing challenging molecular architectures. The product is supplied as a stable adduct to ensure consistent catalytic activity and handling.

Application

• Asymmetric C–H Amination: A key catalyst for the enantioselective insertion of nitrenes into C–H bonds to form chiral amines.
• Enantioselective Cyclopropanation: Enables the synthesis of chiral cyclopropane rings, crucial motifs in active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of chiral drug candidates, particularly for complex, stereochemically defined targets.
• Methodology Development in Organic Chemistry: Serves as a benchmark catalyst in academic and industrial labs for developing new asymmetric transformations.
• Fine Chemical Production: Applicable in pilot-scale and small-volume production of high-value, enantiopure specialty chemicals.

Basic Information

Product Name	Tetrakis[n-Tetrachlorophthaloyl-(S)-tert-Leucinato]Dirhodium Bis(Ethyl Acetate) Adduct
CAS No.	1816286-21-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dirhodium(II) Tetrakis[n-Tetrachlorophthaloyl-(S)-tert-leucinate] Ethyl Acetate Adduct; Rh2(S-TCPTTL)4•(EtOAc)2; Chiral Dirhodium(II) Carboxylate Catalyst; Rh2(S-TCPTTL)4; Asymmetric Dirhodium Catalyst; Dirhodium Tetrakis(α-(tetrachlorophthalimido)-(S)-tert-leucinate); (S)-Dirhodium(II) Tetrakis(α-(tetrachlorophthaloyl)tert-leucinate) Bis(Ethyl Acetate) Adduct
EINECS	Contact for details

Quality Control

Every batch of our chiral dirhodium catalysts is produced and tested under strict quality protocols to ensure exceptional purity and consistent catalytic performance. We employ advanced analytical techniques, including HPLC, NMR, and elemental analysis, to verify identity, enantiomeric purity, and absence of deleterious metal impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and maintain long-term stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Green to dark green crystalline solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Rhodium Content	Contact for details
Solvent Content (Ethyl Acetate)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.