Description

Pyrazine, 2-[(4S)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]- is a high-value, chiral oxazoline-substituted pyrazine derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel therapeutics, agrochemicals, and specialty materials where structural complexity and purity are paramount.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its unique heterocyclic structure can contribute to novel modes of action.
• Ligand Precursor in Catalysis: Serves as a precursor for chiral oxazoline ligands, which are essential in asymmetric catalysis for producing enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or functional additive for creating specialized polymers with tailored electronic or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Pyrazine, 2-[(4S)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-
CAS No.	1814890-52-2
Molecular Formula	C11H15N3O
Molecular Weight	205.26 g/mol
Synonyms	(S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)pyrazine; (4S)-4-(1,1-Dimethylethyl)-2-(2-pyrazinyl)-4,5-dihydrooxazole; 2-[(4S)-4-(tert-Butyl)-4,5-dihydro-1,3-oxazol-2-yl]pyrazine; (S)-4-(tert-Butyl)-2-(pyrazin-2-yl)-4,5-dihydrooxazole; Chiral Pyrazine-Oxazoline Derivative; tert-Butyl Oxazoline Pyrazine; (S)-tert-Butyl Oxazolinyl Pyrazine
EINECS	Contact for details

Quality Control

Our production of Pyrazine, 2-[(4S)-4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, critical for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including chiral HPLC and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.