Description

(2S)-2-Amino-3-(4-Vinylphenyl)Propanoic Acid-Hcl CAS NO 1810074-65-7 is a high-purity, non-natural amino acid derivative featuring a vinylphenyl side chain, making it a versatile chiral building block for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemistry and functional group compatibility in complex molecular architectures. It is primarily utilized in the development of novel pharmaceuticals, peptide-based therapeutics, and specialized materials science applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique, polymerizable vinylphenyl moiety into peptide chains for creating novel biomaterials or drug conjugates.
• Chemical Biology & Proteomics: Serves as a specialty amino acid analog in the study of protein structure, function, and protein-protein interactions through site-specific incorporation.
• Material Science Research: Acts as a monomer or cross-linker precursor in the development of advanced polymers, hydrogels, and smart materials due to its reactive vinyl group.
• Ligand & Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Diagnostic Reagent Development: Utilized in the creation of specialized probes and labeling reagents for imaging and diagnostic assays.

Basic Information

Item	Detail
Product Name	(2S)-2-Amino-3-(4-Vinylphenyl)Propanoic Acid Hydrochloride
CAS No.	1810074-65-7
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	(S)-2-Amino-3-(4-vinylphenyl)propanoic acid hydrochloride; L-4-Vinylphenylalanine hydrochloride; (S)-4-Vinylphenylalanine HCl; (2S)-2-Azaniumyl-3-(4-ethenylphenyl)propanoate chloride; 4-Vinyl-L-phenylalanine hydrochloride; Fmoc-4-Vinyl-L-Phe-OH precursor; Non-natural amino acid derivative
EINECS	Contact for details

Quality Control

Every batch of (2S)-2-Amino-3-(4-Vinylphenyl)Propanoic Acid-Hcl is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles as determined by advanced techniques like HPLC and NMR. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.