Description

4-Bromo-2-Chloro-3-Iodophenol is a highly functionalized halogenated phenol derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists seeking to introduce specific halogen atoms for structure-activity relationship (SAR) studies or to modulate the physical properties of target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a probe or labeling reagent due to its reactive phenolic group and heavy halogen atoms, useful in bioconjugation and imaging studies.
• Organic Synthesis Building Block: Facilitates various cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitutions to create diverse chemical libraries for high-throughput screening.

Basic Information

Product Name	4-Bromo-2-Chloro-3-Iodophenol
CAS No.	1809158-15-3
Molecular Formula	C6H3BrClIO
Molecular Weight	333.35 g/mol
Synonyms	2-Chloro-4-bromo-3-iodophenol; 3-Iodo-4-bromo-2-chlorophenol; Phenol, 4-bromo-2-chloro-3-iodo-; 4-Bromo-2-chloro-3-iodo-phenol; BCI Phenol derivative; Halogenated phenol building block
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-3-Iodophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.