Description

(1S)-1-(5-Chloropyridin-2-Yl)Ethan-1-Amine Dihydrochloride is a high-purity chiral amine derivative, specifically a dihydrochloride salt, designed for advanced chemical synthesis. This compound is valued for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its defined stereochemistry is essential for biological activity. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereoisomers are required for efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new synthetic pathways involving pyridine derivatives.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(1S)-1-(5-Chloropyridin-2-Yl)Ethan-1-Amine Dihydrochloride
CAS No.	1807941-73-6
Molecular Formula	C7H10Cl2N2
Molecular Weight	209.07 g/mol
Synonyms	(S)-1-(5-Chloropyridin-2-yl)ethan-1-amine dihydrochloride; (1S)-1-(5-Chloro-2-pyridinyl)ethylamine dihydrochloride; (S)-1-(5-Chloro-2-pyridyl)ethylamine hydrochloride; (S)-α-Methyl-5-chloro-2-pyridinemethanamine dihydrochloride; (S)-5-Chloro-2-(1-aminoethyl)pyridine dihydrochloride; (S)-1-(5-Chloro-pyridin-2-yl)-ethylamine dihydrochloride; (S)-CPEA dihydrochloride
EINECS	Contact for details

Quality Control

Our (1S)-1-(5-Chloropyridin-2-Yl)Ethan-1-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and compliance with relevant standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.