Description

5-Bromo-3-Fluoro-2-Nitrophenol is a halogenated nitrophenol derivative that serves as a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and pigments, leveraging its nitro and phenolic functional groups.
• Material Science Research: Intermediate for creating functionalized polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags used in biochemical assays and imaging.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing complex aromatic systems.

Basic Information

Product Name	5-Bromo-3-Fluoro-2-Nitrophenol
CAS No.	1807256-50-3
Molecular Formula	C6H3BrFNO3
Molecular Weight	235.99 g/mol
Synonyms	2-Nitro-5-bromo-3-fluorophenol; 3-Fluoro-5-bromo-2-nitrophenol; Phenol, 5-bromo-3-fluoro-2-nitro-; 5-Bromo-3-fluoro-2-nitro-phenol; 1807256-50-3; 5-Br-3-F-2-NO2-PhOH
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Fluoro-2-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature and classification as a strong oxidizer, it must be segregated from incompatible materials such as reducing agents, strong bases, and combustible materials.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.