Description

3-Pyridinecarboxylic Acid, 6-Chloro-2-(Difluoromethoxy)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridine structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modifications. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides, leveraging its halogenated structure for enhanced biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in medicinal and organic chemistry.
• Material Science: Investigated for potential use in the synthesis of specialty polymers and ligands for catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 6-Chloro-2-(Difluoromethoxy)-
CAS No.	1807242-68-7
Molecular Formula	C7H4ClF2NO3
Molecular Weight	223.56 g/mol
Synonyms	6-Chloro-2-(difluoromethoxy)nicotinic Acid; 2-(Difluoromethoxy)-6-chloropyridine-3-carboxylic Acid; 6-Chloro-2-(difluoromethoxy)-3-pyridinecarboxylic Acid; 6-Chloro-2-(difluoromethoxy)pyridine-3-carboxylic Acid; Nicotinic acid, 6-chloro-2-(difluoromethoxy)-; CAS 1807242-68-7
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 6-Chloro-2-(Difluoromethoxy)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.