Description

Benzene, 2-Bromo-1-Fluoro-4-Methyl-3-Nitro- is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific properties such as flame retardancy, chemical resistance, or altered refractive index.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of the bromine atom.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies in organic synthesis, including nucleophilic aromatic substitution and functional group transformations.

Basic Information

Product Name	Benzene, 2-Bromo-1-Fluoro-4-Methyl-3-Nitro-
CAS No.	1806979-49-6
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	2-Bromo-1-fluoro-4-methyl-3-nitrobenzene; 1-Bromo-2-fluoro-5-methyl-4-nitrobenzene; 3-Nitro-2-bromo-1-fluoro-4-methylbenzene; 4-Methyl-2-bromo-1-fluoro-3-nitrobenzene; 2-Bromo-1-fluoro-4-methyl-3-nitro-benzene; Benzene, 2-bromo-1-fluoro-4-methyl-3-nitro-; (2-Bromo-1-fluoro-4-methyl-3-nitro)benzene
EINECS	Contact for details

Quality Control

Our Benzene, 2-Bromo-1-Fluoro-4-Methyl-3-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed in a dry environment to minimize moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.